John S. Kuo, MD, PhD Print Friendly PageFaculty, University of Wisconsin School of Medicine and Public Health
UW Health Clinics
|Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.|
UW School of Medicine and Public Health
|Department of Neurological Surgery|
Professional Certifications and Education
University of Toronto (Labatt Brain Tumor Research Center)
University of Southern California (Norris Comphrehensive Cancer Center)
University of Southern California
University of Southern California
Harvard Medical School, MIT Division of Health Sciences and Technology, Boston, MA
Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.
Dr. Kuo’s research focuses on understanding the genesis of brain tumors, with the goal of developing novel therapies. He has investigated the radiosurgical management of brain tumors and the potential clinical use of novel gene markers in medulloblastomas. The Brain Tumor Research Laboratory is currently focused on the molecular biology of brain tumor stem cells and collaborating with other UW scientists to define possible molecular mechanisms of tumor stem cell pathogenesis to develop novel diagnostic and therapeutic strategies.
Brower JV Clark PA Lyon W Kuo JS .
MicroRNAs in cancer: Glioblastoma and glioblastoma cancer stem cells. Neurochem Int. 2014 Nov;77C:68-77
[PubMed ID: 24937770]
Cong D Zhu W Shi Y Pointer KB Clark PA Shen H Kuo JS Hu S Sun D .
Upregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H+ extrusion, cell migration and survival. Carcinogenesis. 2014 Sep;35(9):2014-24
[PubMed ID: 24717311]
Lyon W Mehta TI Pointer KB Walden D Elmayan A Swanson KI Kuo JS .
Clinton Woolsey: functional brain mapping pioneer. J Neurosurg. 2014 Aug 8;:1-6
[PubMed ID: 25105696]
Weichert JP Clark PA Kandela IK Vaccaro AM Clarke W Longino MA Pinchuk AN Farhoud M Swanson KI Floberg JM Grudzinski J Titz B Traynor AM Chen HE Hall LT Pazoles CJ Pickhardt PJ Kuo JS .
Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy. Sci Transl Med. 2014 Jun 11;6(240):240ra75
[PubMed ID: 24920661]
Pointer KB Clark PA Zorniak M Alrfaei BM Kuo JS .
Glioblastoma cancer stem cells: Biomarker and therapeutic advances. Neurochem Int. 2014 May;71:1-7
[PubMed ID: 24657832]
Anderson BM Khuntia D Bentzen SM Geye HM Hayes LL Kuo JS Baskaya MK Badie B Basavatia A Pyle GM Tomé WA Mehta MP .
Single institution experience treating 104 vestibular schwannomas with fractionated stereotactic radiation therapy or stereotactic radiosurgery. J Neurooncol. 2014 Jan;116(1):187-93
[PubMed ID: 24142200]
Voss J Meier TB Freidel R Kundu B Nair VA Holdsworth R Kuo JS Prabhakaran V .
The role of secondary motor and language cortices in morbidity and mortality: a retrospective functional MRI study of surgical planning for patients with intracranial tumors. Neurosurg Focus. 2013 Apr;34(4):E7
[PubMed ID: 23544413]
Kundu B Penwarden A Wood JM Gallagher TA Andreoli MJ Voss J Meier T Nair VA Kuo JS Field AS Moritz C Meyerand ME Prabhakaran V .
Association of functional magnetic resonance imaging indices with postoperative language outcomes in patients with primary brain tumors. Neurosurg Focus. 2013 Apr;34(4):E6
[PubMed ID: 23544412]
Alrfaei BM Vemuganti R Kuo JS .
microRNA-100 targets SMRT/NCOR2, reduces proliferation, and improves survival in glioblastoma animal models. PLoS One. 2013;8(11):e80865
[PubMed ID: 24244722]
Zorniak M Clark PA Leeper HE Tipping MD Francis DM Kozak KR Salamat MS Kuo JS .
Differential expression of 2',3'-cyclic-nucleotide 3'-phosphodiesterase and neural lineage markers correlate with glioblastoma xenograft infiltration and patient survival. Clin Cancer Res. 2012 Jul 1;18(13):3628-36
[PubMed ID: 22589395]
Clark PA Iida M Treisman DM Kalluri H Ezhilan S Zorniak M Wheeler DL Kuo JS .
Activation of multiple ERBB family receptors mediates glioblastoma cancer stem-like cell resistance to EGFR-targeted inhibition. Neoplasia. 2012 May;14(5):420-8
[PubMed ID: 22745588]
Algharabil J Kintner DB Wang Q Begum G Clark PA Yang SS Lin SH Kahle KT Kuo JS Sun D .
Inhibition of Na(+)-K(+)-2Cl(-) cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells. Cell Physiol Biochem. 2012;30(1):33-48
[PubMed ID: 22759954]
Ranganathan P Clark PA Kuo JS Salamat MS Kalejta RF .
Significant association of multiple human cytomegalovirus genomic Loci with glioblastoma multiforme samples. J Virol. 2012 Jan;86(2):854-64
[PubMed ID: 22090104]
Huang Y Agrawal B Clark PA Williams JC Kuo JS .
Evaluation of cancer stem cell migration using compartmentalizing microfluidic devices and live cell imaging. J Vis Exp. 2011 Dec 23;(58):e3297
[PubMed ID: 22217858]
Upton DC Welham NV Kuo JS Walker JW Pasic TR .
Chronic rhinosinusitis with nasal polyps: a proteomic analysis. Ann Otol Rhinol Laryngol. 2011 Dec;120(12):780-6
[PubMed ID: 22279949]
Baggott CD Einstein MH Miranpuri A Rose SL Kuo JS .
What is the optimal venous thromboembolism prophylaxis for gynecological oncology patients with CNS metastases? Gynecol Oncol. 2011 Nov;123(2):409-10
[PubMed ID: 21807402]
Ebben JD Zorniak M Clark PA Kuo JS .
Introduction to induced pluripotent stem cells: advancing the potential for personalized medicine. World Neurosurg. 2011 Sep-Oct;76(3-4):270-5
[PubMed ID: 21986423]
Miranpuri AS Rajpal S Salamat MS Kuo JS .
Upper cervical intramedullary spinal metastasis of ovarian carcinoma: a case report and review of the literature. J Med Case Rep. 2011 Jul 14;5:311
[PubMed ID: 21756304]
Thomas S Mehta MP Kuo JS Ian Robins H Khuntia D .
Current practices of driving restriction implementation for patients with brain tumors. J Neurooncol. 2011 Jul;103(3):641-7
[PubMed ID: 20972603]
Gondi V Tolakanahalli R Mehta MP Tewatia D Rowley H Kuo JS Khuntia D Tomé WA .
Hippocampal-sparing whole-brain radiotherapy: a "how-to" technique using helical tomotherapy and linear accelerator-based intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1244-52
[PubMed ID: 20598457]