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American Family Children's Hospital
James E. Gern, MD close
James E. Gern, MD

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James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.


Pediatric Allergy, Asthma and Immunology

UW Health Clinics

West Clinic
(608) 263-6180 | (800) 323-8942 | Map
American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

Hospital Affiliation(s)

University of Wisconsin Hospital and Clinics (primary)

UW School of Medicine and Public Health

Department of Medicine

Department of Pediatrics

Professional Certifications and Education

Board Certification Allergy & Immunology
Fellowship Johns Hopkins Hospital, Baltimore, MD
Residency State University of New York, Tufts University, Boston
Internship State University of New York, Syracuse, NY
Medical School University of Southern Florida, Tampa, 1981


Madison Magazine Top Docs 2014

Best Doctors® in America 2014

Best Doctors® in America 2013

Madison Magazine Top Docs 2012

Best Doctors® in America 2011

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.


Our doctors provide a wide range of services. The following list represents some, but not all, of the procedures offered by this physician.

Programs & Conditions

  • Allergic Rhinitis
  • Atopic Dermatitis/Eczema
  • Drug Allergies
  • Food Allergy
  • Immunodeficiency Disorders
  • Insect Sting Allergy
  • Latex Allergies
  • Preschool Wheezing
  • Recurrent Sinus Infection
  • Uticaria

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.

PubMed Articles
Schwantes EA Denlinger LC Evans MD Gern JE Jarjour NN Mathur SK . Severity of virus-induced asthma symptoms is inversely related to resolution IFN-λ expression. J Allergy Clin Immunol. 2015 Mar 14;
[PubMed ID: 25784275]
Jartti T Nieminen R Vuorinen T Lehtinen P Vahlberg T Gern J Camargo CA Jr Ruuskanen O . Short- and long-term efficacy of prednisolone for first acute rhinovirus-induced wheezing episode. J Allergy Clin Immunol. 2015 Mar;135(3):691-698.e9
[PubMed ID: 25129681]
Griggs TF Bochkov YA Nakagome K Palmenberg AC Gern JE . Production, purification, and capsid stability of rhinovirus C types. J Virol Methods. 2015 Feb 24;217:18-23
[PubMed ID: 25724434]
Thomas AO Jackson DJ Evans MD Rajamanickam V Gangnon RE Fain SB Sorkness RL Okupa AY Thomas A Gern JE Lemanske RF Jr . Sex-related differences in pulmonary physiologic outcome measures in a high-risk birth cohort. J Allergy Clin Immunol. 2015 Feb 9;
[PubMed ID: 25678088]
Igartua C Myers RA Mathias RA Pino-Yanes M Eng C Graves PE Levin AM Del-Rio-Navarro BE Jackson DJ Livne OE Rafaels N Edlund CK Yang JJ Huntsman S Salam MT Romieu I Mourad R Gern JE Lemanske RF Wyss A Hoppin JA Barnes KC Burchard EG Gauderman WJ Martinez FD Raby BA Weiss ST Williams LK London SJ Gilliland FD Nicolae DL Ober C . Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nat Commun. 2015 Jan 16;6:5965
[PubMed ID: 25591454]
McGowan EC Bloomberg GR Gergen PJ Visness CM Jaffee KF Sandel M O'Connor G Kattan M Gern J Wood RA . Influence of early-life exposures on food sensitization and food allergy in an inner-city birth cohort. J Allergy Clin Immunol. 2015 Jan;135(1):171-8
[PubMed ID: 25129677]
Ashraf S Brockman-Schneider R Gern JE . Propagation of rhinovirus-C strains in human airway epithelial cells differentiated at air-liquid interface. Methods Mol Biol. 2015;1221:63-70
[PubMed ID: 25261307]
Palmenberg AC Gern JE . Classification and evolution of human rhinoviruses. Methods Mol Biol. 2015;1221:1-10
[PubMed ID: 25261302]
Coleman A Gern JE . Lentiviral hematopoietic stem cell gene therapy in patients with wiskott-Aldrich syndrome. Pediatrics. 2014 Nov;134 Suppl 3:S182-3
[PubMed ID: 25363993]
Lynch SV Wood RA Boushey H Bacharier LB Bloomberg GR Kattan M O'Connor GT Sandel MT Calatroni A Matsui E Johnson CC Lynn H Visness CM Jaffee KF Gergen PJ Gold DR Wright RJ Fujimura K Rauch M Busse WW Gern JE . Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol. 2014 Sep;134(3):593-601.e12
[PubMed ID: 24908147]
Busse WW Gern JE . Asthma and infections: is the risk more profound than previously thought? J Allergy Clin Immunol. 2014 Aug;134(2):260-1
[PubMed ID: 25087225]
Nakagome K Bochkov YA Ashraf S Brockman-Schneider RA Evans MD Pasic TR Gern JE . Effects of rhinovirus species on viral replication and cytokine production. J Allergy Clin Immunol. 2014 Aug;134(2):332-41
[PubMed ID: 24636084]
Bochkov YA Grindle K Vang F Evans MD Gern JE . Improved molecular typing assay for rhinovirus species A, B, and C. J Clin Microbiol. 2014 Jul;52(7):2461-71
[PubMed ID: 24789198]
Wilson MR Naccache SN Samayoa E Biagtan M Bashir H Yu G Salamat SM Somasekar S Federman S Miller S Sokolic R Garabedian E Candotti F Buckley RH Reed KD Meyer TL Seroogy CM Galloway R Henderson SL Gern JE DeRisi JL Chiu CY . Actionable diagnosis of neuroleptospirosis by next-generation sequencing. N Engl J Med. 2014 Jun 19;370(25):2408-17
[PubMed ID: 24896819]
Bousquet J Gern JE Martinez FD Anto JM Johnson CC Holt PG Lemanske RF Jr Le Souëf PN Tepper RS von Mutius ER Arshad SH Bacharier LB Becker A Belanger K Bergström A Bernstein DI Cabana MD Carroll KN Castro M Cooper PJ Gillman MW Gold DR Henderson J Heinrich J Hong SJ Jackson DJ Keil T Kozyrskyj AL Lødrup Carlsen KC Miller RL Momas I Morgan WJ Noel P Ownby DR Pinart M Ryan PH Schwaninger JM Sears MR Simpson A Smit HA Stern DA Subbarao P Valenta R Wang X Weiss ST Wood R Wright AL Wright RJ Togias A Gergen PJ . Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop. J Allergy Clin Immunol. 2014 Jun;133(6):1535-46
[PubMed ID: 24636091]
Wickert LE Karta MR Audhya A Gern JE Bertics PJ . Simvastatin attenuates rhinovirus-induced interferon and CXCL10 secretion from monocytic cells in vitro. J Leukoc Biol. 2014 Jun;95(6):951-9
[PubMed ID: 24532643]
Kloepfer KM Lee WM Pappas TE Kang TJ Vrtis RF Evans MD Gangnon RE Bochkov YA Jackson DJ Lemanske RF Jr Gern JE . Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations. J Allergy Clin Immunol. 2014 May;133(5):1301-7, 1307.e1-3
[PubMed ID: 24698319]
Karta MR Wickert LE Curran CS Gavala ML Denlinger LC Gern JE Bertics PJ . Allergen challenge in vivo alters rhinovirus-induced chemokine secretion from human airway macrophages. J Allergy Clin Immunol. 2014 Apr;133(4):1227-30
[PubMed ID: 24529411]
Obasi CN Barrett B Brown R Vrtis R Barlow S Muller D Gern J . Detection of viral and bacterial pathogens in acute respiratory infections. J Infect. 2014 Feb;68(2):125-30
[PubMed ID: 24211414]
Basta HA Ashraf S Sgro JY Bochkov YA Gern JE Palmenberg AC . Modeling of the human rhinovirus C capsid suggests possible causes for antiviral drug resistance. Virology. 2014 Jan 5;448:82-90
[PubMed ID: 24314639]